The Israeli military said on Tuesday that missiles had been launched from Iran towards Israel, and that its home front command had provided life-saving guidelines to people in various parts of the country.
Earlier, the military had announced that any ballistic missile strike from Iran was expected to be widespread and told the public to shelter in safe rooms in the event of an attack.
The Israeli army also said Israel's airspace was closed following the Iranian attack.
The firing of missiles came after Israeli troops launched ground raids into Lebanon, in the biggest escalation of regional warfare since fighting erupted in Gaza a year ago.
Iran has vowed to retaliate following attacks that killed the top leadership of its Hezbollah allies in Lebanon.
Iran's Revolutionary Guards said the country had launched tens of missiles at Israel, and that if Israel retaliated, Tehran's response would be more crushing.
In Washington, President Joe Biden said the United States was prepared to help Israel defend itself.
Meanwhile, four people were killed and seven wounded in a shooting attack in the Jaffa neighbourhood of Tel Aviv on Tuesday. Israeli police said the two shooters had been "neutralised" and the situation was under control.
Israeli strikes pummelled south Beirut on Monday, Lebanese official media said, while health authorities reported 31 people killed across the country, most of them in the south.
At least one police officer was killed and dozens of people injured in Pakistan as supporters of jailed former Prime Minister Imran Khan clashed with security forces outside the capital Islamabad on Monday, officials and Khan's party said.
A small plane travelling to Costa Rica's capital of San Jose crashed on Monday afternoon, authorities said, killing five of the six passengers on board.
Sectarian fighting in northwestern Pakistan which killed more than 80 people last week restarted on Monday, officials said, breaching a seven-day brokered ceasefire.
A US judge on Monday dismissed the federal criminal case accusing Donald Trump of attempting to overturn his 2020 election defeat after prosecutors moved to drop the case and a second case against the president-elect, citing Justice Department policy against prosecuting a sitting president.