Tens of thousands of people across several cities in Europe and Asia took to the streets to express their solidarity with the Black Lives Matter movement in the US.
Large protests were held in London despite government advice to avoid gatherings due to the risk of coronavirus.
The largely peaceful protests saw people holding placards reading "Black Lives Matter" outside the parliament.
Meanwhile, in the German city of Hamburg, police used pepper spray to disperse large crowds gathered in honour of George Floyd.
Protestors in Paris were also seen ignoring government order to ban demonstrations and gathering at the Place de la Concorde, close to the Embassy.
Protests were also held in Warsaw, Berlin, Brisbane, Sydney, Tokyo, Seoul and Bangkok.
In the US, protestors gathered across several cities for the 12th straight day to demand an end to police brutality and racism.
The Israeli military said on Wednesday its forces resumed ground operations in the central and southern Gaza Strip, as a second day of airstrikes killed at least 48 Palestinians, according to local health workers.
US President Donald Trump and Ukrainian President Volodymyr Zelenskyy agreed on Wednesday to work together to end Russia's war with Ukraine, in what the White House described as a "fantastic" one-hour phone call.
Serbia's parliament formally accepted the resignation of Prime Minister Milos Vucevic on Wednesday, triggering a 30-day deadline for the formation of a new government or the calling of a snap election.
Six migrants have died and 40 are missing after a shipwreck off the Italian island of Lampedusa late on Tuesday, Italy's main news agency ANSA reported on Wednesday.
Israeli airstrikes pounded Gaza and killed more than 400 people on Tuesday, Palestinian health authorities said, shattering nearly two months of relative calm since a ceasefire began, as Israel warned the onslaught was "just the beginning."